Dapoxetine (International)

Poxet should be taken only when sexual activity is anticipated. Poxet must not be taken more frequently than once every 24 hours.

Usage Instructions

This can cause problems for the man and may cause problems in sexual relationships. Dapoxetine HCl belongs to a group of medications called 'selective serotonin reuptake inhibitors' (SSRIs). This medicine increases the time it takes to ejaculate and can improve the control over the ejaculation, sildenafil and dapoxetine which in turn may reduce the frustration or worry about fast ejaculation. © Clearsky Pharmacy( ) Poxet (Generic Dapoxetine Hydrochloride Tablets) Active Ingredient The active ingredient contained in Poxet tablets is Dapoxetine Hydrochloride. © Clearsky Pharmacy( ) Poxet (Generic Dapoxetine Hydrochloride Tablets) Chemical Structure The structure of Dapoxetine Hydrochloride is given below: © Clearsky Pharmacy( ) Poxet (Generic Dapoxetine Hydrochloride Tablets) Poxet Tablets are manufactured by Sunrise Remedies Private Limited, India in the strengths of of 30 mg, 60 mg and 90 mg.

Phosphodiesterase 5 inhibitors

(Website: URL: © Clearsky Pharmacy( ) Poxet (Generic Dapoxetine Hydrochloride Tablets) Dapoxetine Hydrochloride Tablets – Brand Names Dapoxetine Hydrochloride tablets are available under various Drug trade names that include Priligy, Poxet, Dapox, Dasutra, Duralast, Ejalong, Kutub and Sustinex. © Clearsky Pharmacy( ) Poxet (Generic Dapoxetine Hydrochloride Tablets) Uses of Poxet Tablets Poxet (Generic Dapoxetine Hydrochloride Tablets) is a treatment for men 18 to 64 years old with frequent premature ejaculation (PE), which troubles the man and affects the relationship with his sexual partner. PE is a common medical condition in which ejaculation happens with minimal sexual stimulation before, on, or shortly after penetration, and before the man wishes it. Dapoxetine Hydrochloride is a selective serotonin reuptake inhibitor medicine which has specially been developed for the treatment of premature ejaculation. It increases the time it takes to ejaculate and can improve the control over the ejaculation. © Clearsky Pharmacy( ) Poxet (Generic Dapoxetine Hydrochloride Tablets) Poxet Dosage The dosage of Poxet tablets (Generic Dapoxetine Hydrochloride Tablets) for adult men (aged 18 to 64 years) is given below: If the individual response to 30 mg is insufficient and the patient has not experienced moderate or severe adverse reactions or prodromal symptoms suggestive of syncope, the dose may be increased to a maximum recommended dose of 60 mg taken as needed approximately 1 to 3 hours prior to sexual activity.

The incidence and severity of adverse events is higher with the 60 mg dose. If the patient experienced orthostatic reactions on the starting dose, no dose escalation to 60 mg should be performed.

Final Thoughts

There were no unexpected events of overdose is reported with daily doses up to 240 mg (two 120 mg doses given 3 hours apart). In general, symptoms of overdose with SSRls include serotonin-mediated adverse reactions such as somnolence, gastrointestinal disturbances such as nausea and vomiting, tachycardia, tremor, agitation and dizziness. In cases of overdose, standard supportive measures should be adopted as required. Due to high protein binding and large volume of distribution of Dapoxetine, forced diuresis, dialysis, hemoperfusion and exchange transfusion are unlikely to be of benefit. No specific antidotes for Dapoxetine are known.

Frequently Bought Together

Store in a cool & dry place protected from light. Keep away from the reach of children. Dapoxetine, a new antidepressant, has been found to be safe and effective for the treatment of premature ejaculation, according to two major clinical trials. Dapoxetin is a short-acting selective serotonin reuptake inhibitor (SSRI). It is not uncommon for SSRIs to be used off-label for premature ejaculation.

Getting rid of any unwanted medicine

Experts doubt it will be approved by the FDA shortly because SSRIs come with undesirable side-effects after long-term use, dapoxetine spain such as psychiatric problems, dermatological reactions, increase in body weight, lower sex-drive, nausea, headache, upset stomach and weakness. Dr. Jon Pryor, head researcher, University of Minnesota, said that Dapoxetine lengthened ejaculation time and also gave patients more control over ejaculation. You can read about this in the journal The Lancet. The research team examined the results of two trials, totalling 2,614 men. © Clearsky Pharmacy( ) Poxet (Generic Dapoxetine Hydrochloride Tablets) Contraindications Poxet tablets are contraindicated in persons with a hypersensitivity (allergy) to Dapoxetine Hydrochloride or any of the other ingredients of this medicine.

• Dapoxetine 30mg tablets help improve control over ejaculation in many users.
• The onset of action usually occurs within 30 to 60 minutes after ingestion.
• Effects last for approximately 4 to 6 hours post-dose.
• Not a treatment for erectile dysfunction, only premature ejaculation.
• Should not be combined with nitrates or alpha-blockers due to low blood pressure risk.
• Avoid operating machinery if dizziness or drowsiness develops after taking dapoxetine.
• Inform your healthcare provider if you have liver or kidney disease.
• Report any allergic reactions or severe side effects immediately.

Poxet tablets are also contraindicated in patients with significant pathological cardiac conditions, for concomitant treatment with monoamine oxidase inhibitors (MAOIs), or within fourteen days of discontinuing treatment with an MAOI, concomitant treatment with Thioridazine, or within 14 days of discontinuing treatment with Thioridazine, concomitant treatment with serotonin reuptake inhibitors , concomitant treatment with potent CYP3A4 inhibitors such as Ketoconazole, Itraconazole, Ritonavir, Saquinavir, Telithromycin, Nefazodone, Nelfinavir, Atazanavir, etc. Poxet is also contraindicated in patients with moderate and severe hepatic impairment. © Clearsky Pharmacy( ) Poxet (Generic Dapoxetine Hydrochloride Tablets) Storage Instructions Poxet (Generic Dapoxetine Hydrochloride Tablets) have to be stored at controlled room temperature i.e. from 20°C to 25°C (68°F to 77°F) with excursions permitted between 15° to 30°C (59° to 86°F).

Safety Advices

It starts to work very quickly, so it is taken when you anticipate having sex, rather than every day. You have to take it 1 to 3 hours before you have sex. © Clearsky Pharmacy( ) Poxet (Generic Dapoxetine Hydrochloride Tablets) Poxet Dosage The dosage of Poxet tablets (Generic Dapoxetine Hydrochloride Tablets) for adult men (aged 18 to 64 years) is given below: The recommended starting dose for all patients is 30 mg, taken as needed approximately 1 to 3 hours prior to sexual activity. Treatment with Poxet (Generic Dapoxetine Hydrochloride tablets) should not be started with the 60 mg dose. Poxet is not intended for continuous daily use. Keep this as well as all other medicines away buy cheap dapoxetine from children and pets.

• The drug's pharmacokinetics are linear.
• This means doubling the dose doubles the exposure.
• Tolerability often decreases with higher exposure.
• The 30mg dose is a compromise for many.
• Individual metabolism genetics can influence response.
• Pharmacogenomic testing is not currently standard.
• Future personalized medicine may guide dosing.
• It is not radioactive and does not involve imaging.
• It will not set off metal detectors or airport scanners.
• It is not a banned substance in most professional sports.
• Athletes should check with their sports federation.
• The World Anti-Doping Agency list should be consulted.

© Clearsky Pharmacy( ) Poxet (Generic Dapoxetine Hydrochloride Tablets) Warnings Poxet (Generic Dapoxetine Hydrochloride Tablets) is only indicated in men with Premature Ejaculation who meet all the criteria listed in sections. Poxet should not be prescribed to men who have not been diagnosed with Premature Ejaculation.

Before treatment, subjects with other forms of sexual dysfunction, including erectile dysfunction, should be carefully investigated by physicians. Before treatment initiation, a careful medical examination including history of orthostatic events should be performed by the physician.

Brief Description

All the men had from moderate to severe premature ejaculation – on average, the men were ejaculating within one minute of penetration. Half of them were randomly selected to receive Dapoxetine while the other half received a placebo. Both groups had to take their medication from 1 to 3 hours before sexual intercourse. After three months, the men taking a 30-milligram dose of dapoxetine took an average 2.78 minutes to ejaculate after penetration, those on a 60-milligram dose took 3.32 minutes. The placebo group averaged 1.75 minutes (after three months).

Cite this article

Dapoxetine was rejected by the FDA last year. In lay terms it means ‘coming too quickly’ (for a man). The man ejaculates sooner than he or his partner would like. It is common for this to happen now and again. It is seen as a problem for many men and some of their partners if this happens regularly.

Pregnancy and breastfeeding

It is the most common male sexual dysfuntion – estimated to affect about 20% of males in the USA aged 18-59. The problem is thought to be psychological. Primary Premature Ejaculation The man has experienced premature ejaculation throughout his sexually active life. Secondary Premature Ejaculation The condition has developed after the man used to have satisfying sex without ejaculatory problems. — Various treatment options for premature ejaculation — Easy-to-understand information about premature ejaculation at the Mayo Clinic web site “Efficacy and tolerability of dapoxetine in treatment of premature ejaculation: an integrated analysis of two double-blind, randomised controlled trials” The Lancet 2006; 368:929-937 You will need to subscribe to the Lancet to view the article online Written by: Christian Nordqvist Editor: Medical News Today © Clearsky Pharmacy( ) Poxet (Generic Dapoxetine Hydrochloride Tablets) © Clearsky Pharmacy( ) Poxet (Generic Dapoxetine Hydrochloride Tablets) Poxet (Generic Dapoxetine Hydrochloride Tablets) is used to treat premature ejaculation (PE) in men 18 to 64 years of age, who have persistent or recurrent ejaculation with minimal sexual stimulation before, on, or shortly after penetration and before the patient wishes and marked personal distress or interpersonal difficulty as a consequence of PE and poor control over ejaculation. An orthostatic test should be performed before initiating therapy (blood pressure and pulse rate, supine and standing). In case of a history of documented or suspected orthostatic reaction, treatment with Poxet should be avoided. Antidepressants, including SSRIs, increased the risk compared to placebo of suicidal thinking and suicidality in short-term studies in children and adolescents with Major Depressive Disorder and other psychiatric disorders. © Clearsky Pharmacy( ) Poxet (Generic Dapoxetine Hydrochloride Tablets) Warnings Patients should be cautioned to avoid situations where injury could result, including driving or operating hazardous machinery, should syncope or its prodromal symptoms such as dizziness or lightheadedness occur. Possibly prodromal symptoms such as nausea, dizziness/lightheadedness, and diaphoresis were reported more frequently among patients treated with Dapoxetine Hydrochloride tablets compared to placebo.